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The story evolves around the Estrada family, which consists of a big brother Augusto and his three younger  sisters who he has been taking care of since the death of their parents. The eldest sister Silvia "the general" is married with two kids. The middle one Lisa "the perfect" is a nurse at the community hospital. The little one Beatriz @ Beba "the baby" is 16 of age. Their lives have always been like well-oiled machines, but when  Augusto gets married, Silvia gets a job, Lisa falls in love and Beba faces her adolescence crisis, things start to change...

The Family Trees
To help you understand the structure of the families

Daily Summaries
An episode a day.. detailed narration for Mis Tres Hermanas lovers
Malay Summaries     English Summaries

Spoof Centre
A fan's creative version of Mis Tres Hermanas dialogues
Santiago and Margarita     Santiago and Lisa      Augusto, Lisa and Jaime

Nitpick Centre
How illogical and funny can Mis Tres Hermanas be?
The Roles     The Actions     The Scenes