The story evolves around the Estrada family, which consists of a big brother Augusto and his three younger sisters who he has been taking care of since the death of their parents. The eldest sister Silvia "the general" is married with two kids. The middle one Lisa "the perfect" is a nurse at the community hospital. The little one Beatriz @ Beba "the baby" is 16 of age. Their lives have always been like well-oiled machines, but when Augusto gets married, Silvia gets a job, Lisa falls in love and Beba faces her adolescence crisis, things start to change...
The Family Trees